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The Downside Of Microtubule Stability - Study Shows Stalled Microtubules Might Be Responsible For Some Cases Of Charcot-Marie-Tooth Disease
Stalled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth (CMT) disease, Tanabe and Takei report in the June 15, 2009 issue of the Journal of Cell Biology. A mutant protein makes the microtubules too stable to perform their jobs, the researchers find.
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Three Organizations Form Alliance To Address Global Malnutrition
"Three internationally known organizations based in St. Louis - the Donald Danforth Plant Science Center, the Washington University School of Medicine and St. Louis Children"s Hospital" - have entered into a partnership, known as the Global Harvest Alliance (GHA), which aims to "create inexpensive, nutritionally complete food to help the world"s hungry and undernourished," the AP/Google.com reports. Alliance researchers will focus on several of the most successful approaches used to combat malnutrition and attempt to further enrich foods already used to fight it. "In addition, the alliance aims to help testing and distribution of crops genetically modified to boost nutritional content. They hope to provide the crops cheaply to farmers to produce more nutritious foods," writes the AP/Google.com (Taylor, 7/29).
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PanGenetics Receives Approval For Clinical Evaluation Of Anti-NGF Antibody In Patients With Chronic Pain
PanGenetics B.V. announced that the Competent Authority of the Netherlands has approved the Clinical Trials Application for a first-in-man study with antibody PG110. This humanized antibody is a member of the class of Nerve Growth Factor (NGF) inhibitors which represent a promising novel approach in the treatment of chronic pain. PG110 will be evaluated in patients suffering from pain caused by osteoarthritis (OA). The clinical trial is designed as a double blind, placebo controlled study and will be conducted in a single site in Utrecht, the Netherlands, in collaboration with Kendle International.
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Healthcare Costs For U.S. Companies Seen Rising Nine Percent

"Healthcare costs for U.S. businesses are seen rising by 9 percent in 2010, according to a PricewaterhouseCoopers PWC.UL survey, which showed that employers will expect workers to pay more of the bill," Reuters reports. "PwC"s annual "Behind the Numbers: Medical Costs Trends for 2010," released on Thursday, showed that one of the factors driving costs was more workers using health insurance plans if they expected to be laid off. And, it showed that as unemployment rises in the United States, leaving more people uninsured or underinsured, there will be a decline in membership in commercial plans and greater dependence on public programs, such as Medicaid." Of the 500 employers surveyed, 42 percent said they "would increase workers" share of healthcare costs," and 41 percent that they "would increase medical cost sharing through changes to plans." In addition, "more than two-thirds of employers offer wellness and disease management programs, but few said they were very effective at lowering costs." Meanwhile, "costs for healthcare products and services have risen by 9.2 percent in 2009 after rising 9.9 percent in 2008." Jack Rodgers, "managing director in the health policy economics group of PricewaterhouseCoopers," says "The recession is creating a tug of war between upward and downward pressures on medical costsò€¦ With most prices holding steady or falling, health plans will put pressure on providers to hold the line on medical costs" (Ng, 7/13). NPR reports that "more companies are putting health care clinics in the workplace," which some studies show "can cut health care costs by up to 30 percent." Michael Ratcliffe of the consulting firm Fuld and Company "says more than 1,000 U.S. companies have onsite health clinics with doctors, nurses and labs. And many offer 30-minute visits. He estimates that clinics like these will serve 10 to 15 percent of the working population within the next few years." Ted Epperly, president of the American Academy of Family Physicians, points out that most employees still have private doctors, and medical records from job site clinics usually do not "follow patients from place to place" (Toner 7/13). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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