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Managing Erosion Caused By Everyday Beverages
Researchers have warned people to beware of the damage that acidic beverages have on teeth. Yet, for some, the damage and problems associated with drinking sodas, citric juices or certain tea may have already begun to take effect. The question remains: What can be done to restore teeth already affected?
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U.S. To Commit Additional $1B To H1N1 Vaccine Development
HHS Secretary Kathleen Sebelius said Sunday the U.S. has agreed to put an addition $1 billion towards ingredients for the production of a vaccine that offers protection against the H1N1 (swine flu) virus, Reuters reports. "There"ll be another $1 billion worth of orders placed to get the bulk ingredients for an H1N1 vaccination. Congress has agreed with the president that this is the number one priority, keeping Americans safe and secure," Sebelius said (7/12).
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New Cognitive Screening Test For Detecting Early Dementia
Researchers at Addenbrook"s Hospital in Cambridge published a study on bmj.com in which they explain their design and evaluation of a new cognitive test for detecting Alzeimer" disease called TYM ("test your memory") which is considered quicker and more precise than many existing tests, and which can also help diagnose early dementia.
Diagnostics

Is Somatic Hypersensitivity A Predictor Of Irritable Bowel Syndrome?

Although visceral hypersensitivity is considered a hallmark feature of IBS, conflicting evidence exists regarding somatic hypersensitivity in this patient population. Several investigators have found no evidence for heightened somatic pain sensitivity in IBS patients. Also, others have reported similar cold presser pain tolerance in IBS patients and controls. These conflicting findings may result from differing somatic pain testing procedures. Previous studies have explored the correlates of visceral hypersensitivity among patients with IBS. To further evaluate somatic hyperalgesia among patients with IBS, the authors evaluated thermal pain sensitivity among patients with diarrhea-predominant IBS (D-IBS) vs constipation-predominant IBS (C-IBS) compared with healthy subjects. A research led by G Nicholas Verne from United States addressed this issue. The article was published on July 14, 2009 in the World Journal of Gastroenterology. A total of 42 cases with D-IBS and 24 with C-IBS, and 52 control subjects were collected in the study. Their thermal pain hypersensitivity were examined Thermal stimuli were delivered using a Medoc Thermal Sensory Analyzer with a 3 cm - 3 cm surface area. Heat pain threshold (HPTh) and heat pain tolerance (HPTo) were assessed on the left ventral forearm and left calf using an ascending method of limits. The Functional Bowel Disease Severity Index (FBDSI) was also obtained for all subjects. The research revealed controls were less sensitive than C-IBS and D-IBS with no differences between C-IBS and D-IBS for HPTh and HPTo. Thermal hyperalgesia was present in both groups of IBS patients relative to controls, with IBS patients reporting significantly lower pain threshold and pain tolerance at both test sites. A unique finding of this study is that the authors detected a strong relationship between heat pain measures and Functional Bowel Disease Severity Index (FBDSI) scores. IBS patients with high FBDSI scores had the highest thermal pain sensitivity compared to those IBS patients with low to moderate FBDSI scores. Reference: Zhou Q, Fillingim RB, Riley JL, Verne GN. Thermal hypersensitivity in a subset of irritable bowel syndrome patients. World Journal of Gastroenterology 2009; 15(26): 3254-3260. http://www.wjgnet.com/1007-9327/15/3254.asp Correspondence to: G Nicholas Verne, MD, Division of Gastroenterology, Hepatology, and Nutrition, Ohio State University, 288A Office Tower, 395 West 12th Avenue, Columbus, OH 43210, United States. Lai-Fu Li World Journal of Gastroenterology


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