Categories
Cardiovascular
Diagnostics
Endocrinology
Health Insurance
Medical Devices
Mental Health
Nutrition
Oncology
Public Health
Sexual Health
Popular Articles
Cellulite Cream

Columnists Discuss HIV Statistics, National Testing Day
"It"s getting harder to convince people of the urgency, that knowing your HIV status is better than not knowing, that this is still a serious problem," columnist Wendi Thomas writes in the Memphis Commercial Appeal. She writes that some people "assume being HIV positive is no big deal" because former National Basketball Association player Earvin "Magic" Johnson has lived with HIV since 1991 and appears to be healthy. "But if you are HIV positive and delay finding out, the virus could progress" to a point where it becomes "much more difficult to treat," Thomas adds (Thomas, Memphis Commercial Appeal, 6/25). Philadelphia Inquirer columnist George Curry today discussed HIV statistics and findings from a recent Kaiser Family Foundation survey that looked at U.S. residents" views on HIV/AIDS. He said, "It"s time to refocus our attention on HIV and AIDS. And a good way to do that is by getting tested tomorrow" on National HIV Testing Day (Curry, Philadelphia Inquirer, 6/26).
generic viagra online
ECRI Institute Calls For Allocating Comparative Effectiveness Funds For A National Patient Library
In testimony before the Listening Panel of the Federal Coordinating Council for Comparative Effectiveness Research (FCCC) on June 10, 2009, ECRI Institute President and Chief Executive Officer Jeffrey C. Lerner, Ph.D., called for devoting a substantial proportion of the $1.1 billion allocated to the comparative effectiveness research to go toward establishing a National Patient Library™. ECRI Institute® (http://www.ecri.org) is an independent nonprofit organization that researches the best approaches to improving patient care.
News of the day
Swine Flu Update, UK
On Wednesday 3 June 2009 the situation in the UK was as follows:
Public Health

Relationship Between Bone Density And Erosion In Arthritis

Rheumatoid arthritis (RA), the most common form of inflammatory arthritis, affects almost three percent of people over age 65. RA patients experience pain, functional limitations and two forms of disabling bone disease: focal erosions and osteoporosis. After five years of disease, up to 50 percent of RA patients show evidence of focal erosions and RA doubles the risk of osteoporosis and fractures. A new study examined the relationship between these two RA-related processes, in the hopes of providing insight into the underlying pathophysiology of RA-related bone disease. The study was published in the June issue of Arthritis & Rheumatism. Led by Daniel H. Solomon of Brigham and Women"s Hospital in Boston , the study involved 163 postmenopausal women with RA, none of whom were taking osteoporosis medications. Participants underwent bone density scans of the hip and spine, as well as X-rays of the hand to determine if they had bone erosions. The results showed that hip bone mineral density (BMD) correlated with bone erosion, but the relationship was not statistically significant after adjusting for clinical factors such as age, BMI and use of oral glucocorticoids used to treat RA. The relationship did appear stronger, however, in patients with early RA. "Our findings suggest that the relationship between focal erosions and generalized osteoporosis is complicated and modified by many aspects of RA and other factors," the authors state. They point out that with longer disease duration, other variables such as the use of disease-modifying antirheumatic drugs (DMARDs), disease activity and markers of inflammation may dilute the relationship between focal erosions and hip BMD. As to why there was a stronger relationship between hip BMD and erosions than with spine BMD, there are several possible explanations. It"s possible that the inflammation underlying RA affects the hip more than the spine or that the effects are more apparent at the hip, which may more closely relate to joint mobility and overall functional status. Several prior studies have examined the bone manifestations of RA, but the current study is one of the only ones to date that has focused on the relationship between two skeletal manifestations of the disease. The authors note that almost all participants were taking DMARDs, which may blunt the relationship between erosions and BMD. Also, patients were not currently taking glucocorticoids or osteoporosis medications but may have in the past, which might have had an effect on the results. Supplemental vitamin D use may also have had an unforeseen effect. "It may be that the presumed association between erosions and BMD is most relevant with regard to patients with severe or early untreated RA," the authors conclude. This could become increasingly important as more bone-directed treatments become part of RA treatment protocols. For example, data from trials of a monoclonal antibody directed at a molecule important in bone metabolism suggest that it may be effective at improving BMD and reducing progression of erosion. Since focal erosions and osteoporosis may be manifestations of a similar inflammatory response, further studies may clarify important roles of inflammation in both of these processes in RA. Article: "The Relationship Between Focal Erosions and Generalized Osteoporosis in Postmenopausal Women with Rheumatoid Arthritis," Daniel H. Solomon, Joel S. Finkelstein, Nancy Shadick, Meryl S. LeBoff, Carl S. Winalski, Margaret Stedman, Roberta Glass, M. Alan Brookhart, Michael E. Weinblatt, Ellen M. Gravallese, Arthritis & Rheumatism, June 2009. Sean Wagner Wiley-Blackwell


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):

© Copyright 2009