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Experimental Drug Five Times More Effective Against MDR-TB Than Conventional Therapy
A Johnson & Johnson-run study found that its experimental drug TMC207 could make conventional tuberculosis treatment five times more effective against multi-drug resistant TB (MDR-TB) because it cleared traces of the TB bacteria in the sputum of 48 percent of study volunteers after eight weeks, Reuters reports (Emery, Reuters, 6/3). The results were published on Wednesday in the New England Journal of Medicine.
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Some Experts Remain Skeptical Of Withdrawal Method, Despite Recent Study On Effectiveness
Reproductive health experts were "taken aback" by a recent study that found that the withdrawal method is nearly as effective as male condoms in preventing pregnancy, the New York Times reports. The paper -- published in the June issue of the journal Contraception -- found that 4% of couples will become pregnant over a one-year period if they consistently use the withdrawal method, compared with about 2% of couples that consistently use condoms. According to the study"s authors, a more significant finding was that the rate of "typical use" for withdrawal leads to pregnancy 18% of the time, compared with 17% of the time for typical use of condoms. They wrote in the study that "it is unfortunate that some couples do not realize they are substantially reducing their risk of pregnancy when using withdrawal, as these misperceptions may cause unnecessary levels of anxiety. More speculatively, if more people realized that correct and consistent use of withdrawal substantially reduced the risk of pregnancy, they might use it more effectively." Although the authors said the goal of the paper was to encourage discussion, some experts are concerned that spreading a message that withdrawal is effective could lead young people to have unprotected sex, potentially exposing themselves to sexually transmitted infections that can be prevented through condom use, the Times reports. Melissa Gilliam, chief of family planning and contraceptive research at the University of Chicago"s Department of Obstetrics and Gynecology and a board member of the Guttmacher Institute, said the study"s data "don"t necessarily translate to youth today." She added, "In terms of a reliable method used over and over again, the risk of failure is quite high."Rachel Jones, the lead author of the study and a senior research associate at Guttmacher, said that dismissing the withdrawal method as a "legitimate" form of contraception is "counterproductive for the prevention of pregnancy and also discourages academic inquiry into this frequently used and reasonably effective method." She also said that health educators and providers "should discuss withdrawal as a legitimate, if slightly less effective, contraceptive method in the same way they do condoms and diaphragms." She noted that "most women have used withdrawal at some point in their lives."The study"s authors decided to examine the issue after noticing that many researchers and providers "just kind of dismiss withdrawal and don"t seem to realize that it can prevent pregnancy," according to Jones. She added, "Most people seem to be under the impression that you might as well do nothing." Martha Kempner, vice president for information and communications at the Sexuality Information and Education Council of the United States, said the results of the study have "made some classroom teachers nervous to give out the truth in this instance, but we do have to tell the truth." She added, "People, kids in particular, they"re using it. It is better than nothing, and it is always available" (Belluck, New York Times, 7/21).
Mental Health

South Pole Doctor And Cancer Survivor Who Treated Herself 10 Years Ago Dies

A US doctor who diagnosed and treated herself for breast cancer while stationed in the South Pole during the winter of 1999, was then rescued and survived, has died. Dr Jerri Nielsen FitzGerald, aged 57 and a native of Ohio, died at her home in Southwick, Massachusetts, on Tuesday her husband Thomas FitzGerald told the press. Nielsen"s cancer came back in 2005, this time in her brain, said a CBS3 report. She came to prominence as a cancer survivor and campaigner after discovering a lump in her breast while stationed at the National Science Foundation"s Amundsen-Scott South Pole Station in the winter of 1999. She was the only doctor attending the 41-person research team on the site. The weather was too fierce and cold to allow a rescue, so guided by emails and teleconferences with doctors in the US and the help of non-medical staff at the station she carried out her own biopsy. Nielsen, an emergency room doctor from Cleveland, Ohio, showed a welder how to do a needle biopsy. They practised on a raw chicken, according to an article in the Detroit Free Press a few months ago. The US Air Force delivered her anti-cancer drugs by parachute in July, and she was rescued by the Air National Guard in October, reported the Associated Press. In the meantime, while treating herself with chemo drugs, Nielsen continued her duties as the only doctor on the station. Her cancer went into remission and she wrote a best seller about her ordeal titled "Ice Bound: A Doctor"s Incredible Battle for Survival at the South Pole". The book was made into a TV film. She also spent the next ten years as a speaker, talking about how cancer had changed her life, and worked as an ER doctor in various hospitals in the northeast US. In 2006 Nielsen said in an interview with the magazine Psychology Today that her experience at the South Pole helped her to accept things that many people are deeply scared of. She said she came to "feel that they need not be feared" and that it had a lot to do with "peace and surrender than it did with courage". She told the magazine that being in the South Pole was her great good fortune because it made her think clearly about "what was essential in life". Nielsen said she did not fear death and that after first learning her cancer was back, for about three weeks she went through terror, but then felt "the most incredible peace" come over her. "Now I am very happy and excited about going forward with my life. The metastatic disease is now just another part of me, another thing that has happened to me," she said. Nielsen"s story has inspired lots of people around the world, including those supported by Cancer House for Hope, a non-profit organization based in Springfield, Massachusetts. Their executive director, Cheryl Gorski, told CBS3 that: "She really was an inspiration to all cancer survivors locally, nationally and even around the world." "It is always sad and always affects everyone to hear when someone lost their battle with cancer and I"m sure our groups this evening and for the rest of this week this is what we"ll talk about," she added. Gorsky said that the one thing people learn from Nielsen"s story is "being brave in the face of adversity of cancer or any other battle". "Just be brave. I think that"s one thing we can learn from her," she said. Nielsen"s husband told the media earlier today that "she fought hard and she fought valiantly". "She had the most resilience I have ever seen in anyone," he added. As well as her husband, Nielsen is survived by two brothers, three children and both parents. s: CBS3, AP, CNN. Written by: Catharine Paddock, PhD Copyright: Medical News Today Not to be reproduced without permission of Medical News Today


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