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Schizophrenia: A Genetic Basis
Schizophrenia is a severely debilitating psychiatric disease that is thought to have its roots in the development of the nervous system; however, major breakthroughs linking its genetics to diagnosis, prognosis and treatment are still unrealized. Jill Morris, PhD assistant professor of Pediatrics at Northwestern University"s Feinberg School of Medicine and a researcher in the Human Molecular Genetics Program of Children"s Memorial Research Center studies a gene that is involved in susceptibility to schizophrenia, Disc1 (Disrupted-In-Schizophrenia 1). Two recent publications by Morris and colleagues focus on the role of Disc1 in development, particularly the migration of cells to their proper location in the brain and subsequent differentiation into their intended fate. During development, cells need to properly migrate to their final destination in order to develop into the appropriate cell-type, integrate into the corresponding network of cells and function properly. Disruption of cell migration can lead to inappropriate cell development and function, resulting in disease.
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Senate Confirms Goosby As U.S. Global AIDS Coordinator
The Senate on Friday confirmed President Obama"s U.S. Global AIDS Coordinator nominee Eric Goosby, the San Francisco Chronicle reports. Goosby - who "served previously in the Clinton administration as director of HIV/AIDS policy in the Department of Health and Human Services and as chief adviser to the president on HIV-related issues" - will now "head the U.S. strategy for addressing HIV around the world, and oversee the implementation of the President"s Emergency Plan for AIDS Relief" (PEPFAR), the newspaper writes. Goosby "has more than 25 years of experience treating HIV/AIDS," and most recently served as chief executive officer and chief medical officer of the Pangaea Global AIDS Foundation, which is affiliated with the San Francisco AIDS Foundation, according to the San Francisco Chronicle (Doyle, San Francisco Chronicle, 6/20).
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Changing Paradigms In Hereditary Angioedema: A Focus On Timely Diagnosis And New Therapies
Hereditary angioedema (HAE) is an autosomal dominant disease affecting approximately 10,000 people in the United States. HAE causes recurrent attacks of intense localized edema involving the skin, airway, and visceral organs. While chronic therapy with attenuated androgens or plasmin inhibitors has been the mainstay of HAE therapy, many new therapies for prophylaxis and acute treatment are on the horizon. It is important for physicians to understand the signs and symptoms of patients who present with HAE and to be familiar with the conventional and emerging therapies available to treat them.
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Survey Reveals Public's Concerns About Prescription Medication Overdose Risks Following Death Of Michael Jackson

Survey results released by The American Society of Health-System Pharmacists (ASHP) revealed the effects of publicity around Michael Jackson"s alleged prescription drug misuse. More than 200 pharmacists who work in home, ambulatory, and chronic care practices responded to the survey conducted on July 1, 2009. Twenty-eight percent of pharmacists surveyed said patients are asking more questions about the risks of prescription pain medications since the publicity surrounding Michael Jackson"s death. "While circumstances surrounding Michael Jackson"s cause of death are still speculative, the media attention has opened dialogue about the dangers of prescription drug abuse," said ASHP president Lynnae M. Mahaney, M.B.A., FASHP. "Medications can make a tremendous difference for people suffering with chronic pain and these patients should seek treatment," she adds. "However, these medications are extremely powerful and when used improperly they can cause serious harm, even death." ASHP reminds consumers that pharmacists, especially those in with expertise in pain management and palliative care, can guide therapy that effectively manages pain while minimizing concerns for abuse and addiction. ASHP recommends that consumers take the following steps to ensure the safe use of their medications: - Keep a list of your medications to share with your pharmacist and other health-care providers (know what medicines you are taking and on what frequency, the dose, and how to take the medications), - Use one pharmacy or pharmacies that can access your medication records through interconnected computer systems so all prescription medicines can be checked for interactions, and, - Ask your pharmacist when you have questions about your medications. ASHP also offers My Medicine List® on SafeMedication.com, which allows consumers to easily keep track of medications to help prevent drug interactions and other problems. The American Society of Health-System Pharmacists


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