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Antibody Linked To Chemotherapy Drug Inhibits Ovarian Cancer In Lab
A novel anticancer agent, consisting of a monoclonal antibody linked to a chemotherapy drug, showed substantial antitumor activity in ovarian cancer cell lines and in mice, according to a study published online July 29 in the Journal of the National Cancer Institute.
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Sanofi-aventis And Regeneron Announce Results From Phase 2 Study With Aflibercept (VEGF Trap) In Advanced Ovarian Cancer
Sanofi Aventis (Euronext: SAN and NYSE: SNY) and Regeneron Pharmaceuticals, Inc. (Nasdaq: REGN) announced that advanced ovarian cancer patients with recurrent symptomatic malignant ascites (SMA) receiving aflibercept (VEGF Trap) in a randomized, placebo-controlled Phase 2 study experienced a statistically significant improvement in the primary study endpoint, mean time to first repeat paracentesis (removal of fluid from the abdominal cavity), versus placebo control. Symptomatic malignant ascites is an abnormal build-up of fluid in the abdominal cavity in patients with advanced cancer.
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Cholesterol-Regulating Genes Identified By Scientists
Scientists at the European Molecular Biology Laboratory (EMBL) and the University of Heidelberg, Germany, have come a step closer to understanding how cholesterol levels are regulated. In a study published in the journal Cell Metabolism, the researchers identified 20 genes that are involved in this process. Besides giving scientists a better idea of where to look to uncover the mechanisms that ensure cholesterol balance is maintained, the discovery could lead to new treatments for cholesterol-related diseases.
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Veterinarian Offers Advice On Evacuating With A Pet If Disaster Strikes

A veterinarian at Kansas State University"s College of Veterinary Medicine has advice for pet owners who want to consider how pets fit into their own household emergency plans -- especially if that includes evacuating. Dr. Marjory Artzer, professor of clinical sciences, suggests thinking about the supplies you"d ordinarily have on hand at home but may not have access to if forced to evacuate. This includes pet food, which can be bagged in easy to handle amounts, as well as bottled water, a leash, a pet carrier and an adequate amount of any medications your pet regularly takes. Artzer said heartworm medications and flea/tick preventatives are essential. Pet owners also may want to include bandaging material for wounds. Pets not of the canine or feline variety require considerations in addition to the basics like food and water. Artzer said owners should think about a safe means of transport and a way for environmental temperature control. Artzer also suggests bringing along paperwork like health records and registration. "It may make a difference in how the pet is handled," she said. Having pets properly identified can make an emergency or evacuation go more smoothly, too. "An ID tag on a collar is an easy way to see immediately, but they can get lost," she said. "A permanent way is microchipping." In an emergency, your pet"s nerves can be just as frayed as yours. To make animals more comfortable, Artzer suggests doing a pets" favorite activity every day, whether it"s walking, playing ball or just brushing its fur.The best time to think about an emergency or evacuation plan for your pet is before disaster strikes. Artzer suggests thinking of alternatives to evacuating with your pet ahead of time. "Have a backup plan for help, like a friend or boarding facility," she said. "It is important to think ahead." Kansas State University


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