Endocrinology
A leading UK authority on midwifery told a Sunday newspaper that more women should experience the natural pains of labour unaided by
Colorectal cancer (CRC) is the third leading cause of cancer death in both men and women and the second leading cause of cancer death when both sexes are combined. African Americans have lower survival rates compared to whites. Researchers at Barbara Ann Karmanos Cancer Institute, in Detroit, Michigan in Detroit sought to investigate the effect of demographics, clinical factors and socioeconomic status (SES) on racial disparities in CRC survival in the Detroit Metropolitan Area.
DxS, a personalised medicine company, has had its TheraScreen: K-RAS Mutation Kit granted a licence by the regulatory body Health Canada for use as a diagnostic for anti-EGFR therapies and as the companion diagnostic for Amgen"s colorectal cancer therapy, Vectibix™ (panitumumab).
Scientists at deCODE genetics (Nasdaq: DCGN) and colleagues from Europe and the United States today report the discovery of a common single-letter variant in the sequence of the human genome (SNP) conferring increased risk of atrial fibrillation (AF) and stroke. The findings will be integrated directly into the deCODE AF(TM) reference laboratory test for gauging individual risk of AF and stroke and helping to identify stroke patients who may benefit from enhanced monitoring for AF.
El Salvador and Benin have marked World Asthma Day by placing orders with the Asthma Drug Facility (ADF). Through the ADF these and other low- and middle-income countries will be able to obtain quality-assured essential asthma medicines at affordable prices for the first time.
Research published in the June 26, 2009 edition of Proceedings of National Academy of Sciences provides further evidence for novel roles of tRNA synthetases in disease, validating the therapeutic potential for aTyr Pharma"s new class of naturally occurring protein agents. The aminoacyl tRNA synthetases are universal and essential components of protein synthesis machinery found in all organisms, but human synthetases have naturally occurring resected variants with potent cell signaling activities that are vital to normal functioning of humans. aTyr Pharma"s proprietary product generating engine consists of these resected proteins (resectins) of human aminoacyl tRNA synthetases with cell signaling activities distinct from the protein synthesis activities. In this recently published study, a model of a human neuropathy was created in the fruit fly (Drosophila) by introducing mutations in the tyrosyl-tRNA synthetase which correspond to disease associated mutations in humans. These dominant mutations do not cause a loss in the protein synthesis activity, indicating that the neuropathy arises from distinct activities of this tRNA synthetase. This work provides further proof of noncanonical roles for tRNA synthetases in human disease.
The U.S. Department of Justice and 16 states have joined two whistle-blower lawsuits filed in federal District Court in Massachusetts alleging that Wyeth defrauded the government by not offering the same discounts on two medications to Medicaid that it offered to hospitals, the Wall Street Journal reports. The lawsuits were initiated following a grand-jury investigation by the U.S. Attorney"s Office in Massachusetts (Johnson, Wall Street Journal, 5/19). The other states included in the lawsuits are California, Delaware, Florida, Illinois, Indiana, Louisiana, New York, Michigan, Nevada, New Hampshire, Tennessee, Texas, Virginia, Wisconsin and the District of Columbia (Barrett, AP/Austin American-Statesman, 5/18).According to the lawsuits, Wyeth from 2000 to 2006 sold hospitals a bundled package called the Protonix Performance Agreement, which included its acid-reflux drugs Protonix Oral and Protonix IV. The suits allege that Wyeth gave hospitals up to a 94% discount for the oral version under the deal, with the understanding that when patients were released from hospitals they would be switched from the intravenous version of the drug to the oral version. According to the complaint, Wyeth hoped to gain an edge in a competitive market for acid-reflux pills by taking advantage of its standing as the only company offering an IV acid-reflux drug. The Journal reports that Wyeth charged hospitals $20 per vial for the IV version of Protonix and $3 for the oral version.Medicaid rules stipulate that the program is entitled to the lowest price on prescription drugs, and drugmakers are required to pay states rebates if they offer discounts to any other entities. The lawsuits state that Wyeth avoided paying hundreds of millions of dollars to state Medicaid programs because it did not offer the programs the same discounts or provide rebates (Wall Street Journal, 5/19).The lawsuits are seeking financial penalties against Wyeth of up to three times the amount lost by Medicaid. Assistant Attorney General Tony West said, "By offering massive discounts to hospitals, but then hiding that information from the Medicaid program, we believe Wyeth caused Medicaid programs throughout the country to pay much more for these drugs than they should have." Wyeth spokesperson Doug Petkus said that Wyeth "believes that its pricing calculations were correct and intends to defend itself vigorously in these actions" (AP/Austin American-Statesman, 5/18).
In their first meeting, President Obama and Pope Benedict XVI on Friday discussed their views on abortion, embryonic stem cell research and the rights of health care workers to object to procedures and services that go against their beliefs, the Los Angeles Times reports. During a 30-minute discussion, the pope expressed to Obama his beliefs about "the defense and promotion of life and the right to abide by one"s conscience," according to the Vatican. The Times reports that the statement was a "clear reference" to debates over abortion rights, embryonic stem cell research and "conscience" protections for health care providers who refuse care on moral or religious grounds (Chu, Los Angeles Times, 7/11).According to Time, Benedict showed "no intention of papering over differences on what the Vatican calls "life" issues," including abortion rights. Vatican spokesperson the Rev. Federico Lombardi said that the pope told him how Obama "explicitly expressed his commitment to reducing the number of abortions and to listen to the Church"s concerns on moral issues" (Israely, Time, 7/10). According to White House deputy national security aide Denis McDonough, Obama was "eager to find common ground on these issues and to work aggressively to do that" (Simpson/Feller, AP/Boston Globe, 7/11). However, "[I]t may just be that there"s issues that you can"t come to agreement on," McDonough added, noting that Obama believes that "you can disagree without being disagreeable" (Los Angeles Times, 7/11).Montsignor Georg Ganswein, the pope"s personal secretary, said that Obama was given a copy of "Dignitas Personae," or "The Dignity of a Person," a Vatican document released in December detailing the Roman Catholic Church"s most recent stance on bioethics issues (Time, 7/10). The document "hardened" the Church"s opposition to embryonic stem cell research, cloning and in vitro fertilization (AP/Boston Globe, 7/11). Obama assured the pope he would read the document that day on his flight from Italy to Ghana. Ganswein said that the document "can help the president better understand the position of the Catholic Church." Lombardi noted that it "would be ambiguous to hide or minimize what we believe," adding, "It"s not meant to be divisive or polemical" (Time, 7/10).
President Barack Obama announced his intent to nominate Regina M. Benjamin as Surgeon General, Department of Health and Human Services.
G8 and leaders from Algeria, Angola, Egypt, Ethiopia, Libya, Nigeria, Senegal, South Africa and the African Union on Friday announced an agreement to strengthen their partnership to improve access to water in Africa, Ennahar Online reports (Oudina, 7/10).
Twenty hematology and hematology/oncology fellows and junior faculty will begin a unique year-long education and mentoring program this summer as part of the American Society of Hematology (ASH) Clinical Research Training Institute.
HHS Secretary Kathleen Sebelius said Sunday the U.S. has agreed to put an addition $1 billion towards ingredients for the production of a vaccine that offers protection against the H1N1 (swine flu) virus, Reuters reports. "There"ll be another $1 billion worth of orders placed to get the bulk ingredients for an H1N1 vaccination. Congress has agreed with the president that this is the number one priority, keeping Americans safe and secure," Sebelius said (7/12).
Wall Street Journal: A recent decision by CMS to end Medicare coverage of virtual colonoscopies is "a preview of how health care will be rationed when Democrats" create "a new "universal" health insurance entitlement for the middle class," a Journal editorial states. According to the editorial, the prospects of such a health system are "playing out in miniature in Medicare" where CMS has decided that offering an alternative to the traditional colonoscopy is "too pricey." The editorial states that the situation features "precisely the sort of complexity that the Democrats would prefer to ignore as they try to restructure health care" and use comparative effectiveness research to determine what works best for the majority of patients. According to the editorial, "The problem is that what "works best" isn"t the same for everyone." It continues that CMS "made the hard-and-fast choice that it was cheaper to cut [virtual colonoscopies] ... for all beneficiaries. If some patients are worse off, well, too bad." The editorial concludes that the situation is "merely a preview of the life-and-death decisions that will be determined by politics" if Democrats enact their ideal system (Wall Street Journal, 5/19).
When cells experiencing DNA damage fail to repair themselves, they send a signal to their neighbors letting them know they"re in trouble. The discovery, which shows that a process dubbed the DDR (DNA Damage Response) also controls communication from cell to cell, has implications for both cancer and aging. The findings appear in the July 13 online edition of the Nature Cell Biology.
Research led by The University of Arizona College of Pharmacy has found that medication prescribers correctly identified fewer than half of drug pairs with potentially dangerous drug-drug interactions.
Plans to improve access to occupational health services in Wales to help tackle absenteeism and ill-health in the workplace will be announced today [Tuesday, 14 July] by Health Minister Edwina Hart.
Men aged 35-54 are almost twice as likely to have diabetes compared to their female counterparts, reveals our new report "Diabetes in the UK 2009" out today.
What if you could test your risk for Alzheimer"s disease much like your cholesterol levels - through a simple blood test?
The tiny translucent egg nestled in the special laboratory gel was a mere 30 days old, but its four-week birthday caused researchers to quietly celebrate. This was the first time anyone had successfully grown a woman"s immature egg cells, contained in a tiny sac called a follicle, to a healthy and nearly mature egg in the laboratory. When an egg is fully mature, it is ready to be fertilized.
If that office inkjet printer has become just another fixture, it"s time to take a fresh look at it. Similar technology may soon be used to develop paper-based biosensors that can detect certain harmful toxins that can cause food poisoning or be used as bioterrorism agents.
In the brain, many types of synaptic proteins are spatio-temporally regulated to maintain synaptic activity at a constant level. Here, the Japanese research group led by Professor Masaki Fukata, Drs. Yuko Fukata and Jun Noritake in National Institute for Physiological Sciences, Japan, found that two types of palmitoylating enzymes finely-tune the location and function of a major synaptic protein, PSD-95, in different ways. They also found that this mechanism contributes to keeping synaptic activity stable when synaptic activity dynamically changes. The Japan Science and Technology Agency (JST) supported this study. They report the finding in Journal of Cell Biology published on July 13, 2009.
Anne Arundel County, Md., Executive John Leopold recently appointed 20 community leaders, government officials and health workers to serve on the county"s first HIV/AIDS commission, which aims to understand and develop strategies for addressing the disease, the Baltimore Sun reports. The Sun reports the commission is believed to be the first of its kind in a suburban Maryland county and similar to a commission launched in Baltimore City. Council member Daryl Jones in 2008 proposed legislation to create the commission, citing the increasing number of HIV cases in the northern part of the county, likely because of its close proximity to Baltimore. According to Jones, the commission aims to generate funds for testing and outreach services; address stigma associated with the disease; and heighten awareness of the virus among residents. The commission also will produce an annual report on HIV/AIDS-related issues in the county, Jones said. Anne Arundel County had 1,000 recorded HIV/AIDS cases in 2006, with 56 newly reported HIV cases that year, according to the Maryland AIDS Administration. "It"s pretty much what I would classify as having the potential to reach epidemic proportions," Jones said, adding that Baltimore has the second highest AIDS rate among major metropolitan areas in the country. According to Kelly Sipe Russo, a physician clinical specialist with the county health department"s division of public health, the department has identified "hot spots" in the county with high HIV/AIDS rates, including the northern area and Annapolis. Russo noted that while HIV/AIDS rates in the county are not on the rise, they also are not declining, even with programs in place to increase awareness and provide help for those living with the disease. According to the Sun, although res and staffing are limited for many programs, health department officials still believe the programs are slowly having an effect and that more outreach is needed, especially for testing and treatment. Jones said that the economic downturn could lead more people to drug or alcohol use. He also noted that the stigma surrounding the disease is a major factor behind the creation of the commission. "Part of what the commission will address is figuring out ways to take away some of the fear factor" associated with HIV testing, he said. The Sun also profiled Carolyn Massey, an HIV-positive woman appointed to the commission. She said that stigma associated with the virus still is widespread, adding, "I feel we"re doing some of the right things the right way. HIV infection is something that does not have to happen" (Dixon, Baltimore Sun, 5/18).
Accera, Inc., a biotechnology company delivering breakthrough therapies in central nervous system diseases, today announced further evidence for genetic interactions impacting the efficacy of the ketogenic compound AC-1202 (Axona(TM)) in Alzheimer"s disease. New data from the company"s previously completed double-blind, placebo-controlled trial in patients with mild-to-moderate Alzheimer"s disease demonstrates an interaction between two genetic markers that strongly influence the therapeutic response in patients. Dr. Samuel Henderson, Executive Director of Research, will present these results at the 2009 International Conference on Alzheimer"s Disease (ICAD) sponsored by the Alzheimer"s Association.
Watson Pharmaceuticals, Inc. (NYSE: WPI), a leading specialty pharmaceutical company, announced that it received a Complete Response Letter from the U.S. Food and Drug Administration (FDA) on its New Drug Application (NDA) for TRELSTAR(R) 22.5 mg (triptorelin pamoate for injectable suspension), a 24-week formulation of TRELSTAR(R) for the palliative treatment of advanced prostate cancer. The TRELSTAR(R) NDA was prepared in cooperation with Debiopharm Group, a Swiss-based global biopharmaceutical group of companies.
RNs from the California Nurses Association/National Nurses Organizing Committee (CNA/NNOC) have filed an urgent plea with the state of California to step in and force Sutter Solano Hospital to provide nurses with proper safety equipment when they care for patients infected with the H1N1 "swine flu" virus. The nurses fear that the unsafe procedures at the hospital create a danger of infection for every patient at the facility, as well as for the surrounding community.
Black women ages 20 to 29 are more prone to pack on unhealthy abdominal and visceral fat than Hispanic women the same age, and as compared to their elders, according to researchers from Wake Forest University Baptist Medical Center and colleagues.
The Alliance for Pharmaceutical Care will offer health screenings and present information on vital healthcare issues at "Pharmacist Central", the Alliance"s exhibition at the National Conference of State Legislatures (NCSL) 2009 Legislative Summit, July 20-24 in Philadelphia, Pennsylvania.
Blacks and others with darker skin might be at greater risk for tobacco addiction than whites and those with lighter skin because the greater the amount of melanin, the coloring pigment in skin, the more nicotine appears to be stored, according to preliminary findings published in the journal Pharmacology, Biochemistry and Behavior, the New York Times reports. For the study, lead researcher Gary King, a professor of biobehavioral health at Pennsylvania State University, looked at 150 black smokers and measured their levels of melanin and cotinine, a byproduct of nicotine. They also surveyed the participants to determine the level of their smoking habit. Those with the most melanin were found to smoke the most and have the most cotinine in their system. They also had the highest level of dependence on tobacco. The findings might indicate why some people are more affected by nicotine than others, according to the study (Nagourney, New York Times, 5/19).
A new study has revealed a possible link between smoking and more rapid progression of disability in multiple sclerosis (MS).
"After a series of false starts, House Democrats are finally expected to unveil the details of a sweeping reform measure on Tuesday that would drastically revamp the country"s health care system," Politico reports. "Party leaders had initially planned to introduce legislation last week and start considering it in committees this week. But that timeline was scuttled when a parade of moderates threw up their arms last week at a draft of the bill offered weeks earlier by the three chairmen writing it." While the Democrats "know that the clock is ticking-that the slower the process goes, the more time opponents will have to plant doubts in the minds of voters," Republicans are "feeling giddy-free to stand back and watch as Democrats fight amongst themselves."
Congressional Republicans are pushing an idea unlikely to garner much traction that would force members of Congress who vote for a government-run public plan for health insurance coverage to enroll in it, Politico reports. "Rep. John Fleming (R-La.), a family physician, kicked off the quixotic bid last week, urging House members to give up their right to participate in the much-revered Federal Employees Health Benefits Program if they support a government-run program as part of the health care reform package. Sens. John McCain of Arizona and Tom Coburn of Oklahoma are pushing the same concept in the Senate, preparing separate amendments that would require members - and maybe even their staffs - to sign up for the public option."
"Healthcare costs for U.S. businesses are seen rising by 9 percent in 2010, according to a PricewaterhouseCoopers PWC.UL survey, which showed that employers will expect workers to pay more of the bill," Reuters reports. "PwC"s annual "Behind the Numbers: Medical Costs Trends for 2010," released on Thursday, showed that one of the factors driving costs was more workers using health insurance plans if they expected to be laid off. And, it showed that as unemployment rises in the United States, leaving more people uninsured or underinsured, there will be a decline in membership in commercial plans and greater dependence on public programs, such as Medicaid." Of the 500 employers surveyed, 42 percent said they "would increase workers" share of healthcare costs," and 41 percent that they "would increase medical cost sharing through changes to plans." In addition, "more than two-thirds of employers offer wellness and disease management programs, but few said they were very effective at lowering costs."
New research showing that "a receptor molecule involved in the recognition of HIV-1 responds to the virus differently in women than in men," might "explain why HIV infection progresses faster to AIDS in women than in men with similar viral loads," the HealthDay/Greenville Daily Reflector reports. The study was conducted by researchers at the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University and will be published in an upcoming issue of the journal Nature Medicine. Study authors also note that during the early stages of infection, women tend to have a stronger immune response to HIV than men, but then progress to AIDS more quickly. The different immune system response "then leads to differences in chronic T-cell activation, a known activator of disease progression, according to the researchers," the article states (7/13). Researcher Marcus Altfeld said the findings raise new questions about how sex hormones affect HIV in the body. "Focusing on immune activation separately from viral replication might give us new therapeutic approaches" to treating HIV, he added (AFP/Google News, 7/13).
According a Toronto Star column, it is an "enormous challenge" for India"s government to try to get all of its citizens immunized against polio. "It has used everything from elephants and camels to rickety boats and bikes to ferry the vaccine to remote regions where temperatures have topped 40C the past three months. The polio serum needs to be kept at a temperature below 8C. Its efforts have not all been in vain: the number of new cases in the country last year was 559, down from 200,000 in the early 1980s," writes columnist Rick Westhead.
Scientists at NOAA"s National Centers for Coastal Ocean Science and the Monterey Bay Aquarium Research Institute (MBARI) have successfully conducted the first remote detection of a harmful algal species and its toxin below the ocean"s surface. The achievement was recently reported in the June issue of Oceanography.
People with mental health problems could find themselves without adequate help and support under proposals set out in today"s green paper on adult social care, warns leading mental health charity Rethink.
The University of Florida will receive nearly $26 million over five years to speed the transformation of scientific discoveries into medical advances for patients.
The biopharmaceutical company PAION AG (ISIN DE000A0B65S3; Frankfurt Stock Exchange, Prime Standard: PA8) today announces that the respective Data Monitoring Committees (DMCs), after predefined interim analyses, recommended that the Company should proceed as planned with their Phase IIa study as well as Phase Ib of CNS 7065, a new short-acting intravenous anesthetic/sedative.
Ben-Gurion University of the Negev (BGU) researchers, in a collaboration with colleagues from the University of Leipzig, Germany, have identified a signaling pathway that is operational in intra-abdominal fat, the fat depot that is most strongly tied to obesity-related morbidity.
Young American-raised Asian and Pacific Islanders (API), who are in the sexual minority, face psychological and social stresses in dealing with their families" values and ancestral cultures that significantly impact the development of their ethnic and sexual identities.
Results of a survey published in the July issue of the Journal of the American College of Surgeons show that a large subset of surgical residents consider duty hour regulations (DHR) a significant barrier to their surgical education and express a desire for flexibility to work longer hours than current restrictions allow.
In the July 15th issue of G and D, Dr. Suzanne Baker (St. Jude Children"s Research Hospital) and colleagues report on their surprising discovery of cell-type specificity of PI3K signaling in the mammalian brain. This finding highlights the complexity of this clinically significant cell signaling pathway, and its relevance to the design of small molecule PI3K pathway inhibitors, to both maximize efficacy and minimize side effects.
U.S. House of Representatives Democrats today unveiled their bill for health care reform - the America"s Affordable Health Care Choice of 2009. In response, National Community Pharmacists Association (NCPA) Executive Vice President and CEO Bruce T. Roberts, RPh, issued the following statement:
The following are helpful tips to pet owners offered by veterinarians at Colorado State University?s Veterinary Teaching Hospital. The paragraphs can be used alone as filler or in a group as a set of tips. If you need additional information, please contact Dell Rae Moellenberg at 970-491-6009 or DellRae.Moellenberg@colostate.edu. If you?d like to attribute the information, please attribute it to Colorado State University?s College of Veterinary Medicine and Biomedical Sciences.
A specialty as diverse as urologic nursing requires comprehensive educational offerings that keep nurses up to date in the varied practice areas. The Society of Urologic Nurses and Associates (SUNA) will continue to show its commitment to excellence in clinical practice by hosting its 40th Annual Conference, October 2-5, 2009, at the Hyatt Regency Chicago, in Chicago, IL.
Smith & Nephew"s Advanced Wound Management division (NYSE:SNN) announced that the UK Court of Appeal has ruled as invalid all claims asserted against Smith and Nephew of the patent EP 0 626 720 that is licensed to Kinetic Concepts, Inc. (NYSE: KCI). As a result, the preliminary injunction against Smith & Nephew"s RENASYS(TM)-F NPWT system has been lifted.
Most children who suffer from chronic daily headache may outgrow the disabling condition, according to research published in the July 15, 2009, online issue of Neurology®, the medical journal of the American Academy of Neurology. Nearly 1.5 percent of middle school children are affected by chronic daily headache, which includes chronic migraines and tension-type headaches.
A new Alabama law effective July 1 provides free treatment options for women diagnosed with
A three-judge panel of the U.S. Court of Appeals for the 7th Circuit on Tuesday lifted, an injunction blocking the enforcement of an Illinois law that requires parental notification 48 hours before minors can undergo abortion procedures, the AP/South Town Star reports. The Illinois Legislature originally passed the law in 1984 and revised it in 1995. In 2007, U.S. District Judge David Coar issued an injunction blocking enforcement of the law. On Tuesday, the appeals court said that the measure was "a permissible attempt to help a young woman make an informed choice about whether to have an abortion."The American Civil Liberties Union, which challenged the law, argued that a provision that allows a notification of a judge, rather than a parent, would be unworkable in practice. In an opinion by Judge Richard Cudahy, the appeals court panel said, "We acknowledge that there might be practical problems with the procedure at issue here" and that "it may be intimidating for a minor to navigate the process of presenting her case to a judge, for instance." It continued, "But we fail to see a better alternative. Abortion, no matter how it is confronted, may present intimidating choices to the minor woman who faces it."The law will take effect within a few weeks unless opponents ask for a stay. Ed Yohnka, an ACLU spokesperson, said that it is unclear what the next step would be but that the appeals court could be asked to rehear the case (Robinson, AP/South Town Star, 7/15).
Individuals with heart disease are twice as likely to suffer from depression as the general population, an association the medical community has largely been unable to explain. Now, a new study by researchers at The Miriam Hospital, in conjunction with The Montrē©al Heart Institute, University of Montrē©al and McGill University, reveals there may be genetic variations that contribute to depression in heart disease patients.
Over 80% of rural and remote doctors recently surveyed by the Rural Doctors Association of Australia (RDAA) believe adding a significant rural and remote loading on Medicare items would assist in recruiting and retaining doctors in their communities.
Agriculture Secretary Tom Vilsack and Health and Human Services (HHS) Secretary Kathleen Sebelius commended the Council to Improve Foodborne Outbreak Response (CIFOR) for the new Guidelines for Foodborne Disease Outbreak Response. These guidelines assist local, state and federal agencies in preventing and managing foodborne disease outbreaks through planning, detection, investigation, control and prevention.
GlaxoSmithKline (GSK) on Tuesday announced plans to invest $97 million over 10 years "to improve research, development and access to AIDS drugs in Africa," Reuters reports. GSK also put forth "a new free voluntary licensing agreement for AIDS drug abacavir, or Ziagen with South African generic drugmaker Aspen Pharmacare." According to Reuters, Aspen will be able to "manufacture a cheaper generic version of the drug."
The AP/Lexington Herald-Leader on Tuesday examined the nomination of Alabama physician Regina Benjamin for U.S. Surgeon General by President Obama, the history of the position and how former Surgeon Generals have addressed health issues such as HIV/AIDS (Stobbe, 7/14). According to Advocate.com, "During her speech accepting the nomination, Benjamin acknowledged her familiarity with HIV complications and issues, as her brother died at the age of 44 of an HIV-related illness. Having such a personal experience, especially a loss, due to HIV/AIDS could have a strong impact on her policy and public health campaigns, [Phil Curtis, director of government affairs at AIDS Project Los Angeles], told Advocate.com on Tuesday." The article states, "Curtis said that Benjamin has the ability to reach out to communities that have been largely underserved by efforts to reduce the rate of infection," and she "will also be able to contribute to Congress"s current debate on health care policy, including strategies for early HIV prevention, and accessibility to prescription drugs" (Garcia, 7/14).
NHS clinical teams will have access to data showing their performance against a set of more than 200 indicators of high quality care in the NHS in one place. It is the next phase in the drive to help NHS professionals improve the quality of care they deliver to patients, and will also support providers and commissioners of NHS services.
The capacity to figure out what others are thinking and what they mean is an ability unique to people that"s central to our lives. A new study on the neural mechanisms that govern these abilities sheds light on the relation between how people and groups interact, on the one hand, and how the brain develops and functions, on the other.
Young adolescents care a lot about what others think about them. A new study confirms this using brain-mapping techniques that shed new light on this complex period of social development.
AGA Medical Corporation has received European CE Mark approval for its AMPLATZER® vascular plug, AVP 4. The device, which is indicated for arterial and venous embolizations in the peripheral vasculature, uses AMPLATZER"s proven mesh-braided Nitinol technology and may eliminate the need for catheter exchange, giving physicians a more efficient procedure. AGA Medical will begin marketing the AVP 4 in Europe immediately.
Mentor Capital, Inc. (Pink Sheets:MNTR) announces that Quantum Immunologics, Inc. (QI) has met a significant milestone marking the beginning of its FDA-authorized breast cancer trial, the completion of the first clinical treatment injection.
Amid reports that swine flu viruses are developing the ability to shrug off existing antiviral drugs, scientists in Japan are reporting a first-of-its kind discovery that could foster a new genre of antivirals that sidestep resistance problems, according to an article scheduled for the July 23 issue of the ACS" Journal of the Medicinal Chemistry, a bi-weekly publication.
Four major US national laboratories have worked together to develop a computer model to help airport authorities screen passengers for pandemic influenza. The tool can help estimate false negatives, people with influenza who slip through the screening process, and so assess the risk of infected passengers unknowingly spreading disease across the nation.
Obesity -- that never-ending "battle of the bulge"-- dates back to the Stone Age and yet is emerging today as a modern health epidemic. While its root cause is as simple as calories consumed versus calories burned, it"s cure is knotted somewhere in a complex web of biology, psychology and culture.
The California Institute of Quantitative Biosciences (QB3) has joined with the City of San Francisco and FibroGen Inc to launch the QB3 Mission Bay Incubator Network, to spur growth in the bioscience industry.
The president of the American College of Physicians (ACP) told the chairmen of the House Ways and Means, Energy and Commerce, and Education and Labor Committees that America"s Affordable Health Choices Act of 2009, H.R. 3200, is "closely aligned" with ACP policies on coverage, workforce, and payment and delivery system reform.
Chinese researchers have unlocked the mechanism of an emerging mind-body technique that produces measurable changes in attention and stress reduction in just five days of practice.
Sapient (NASDAQ: SAPE) announced that it has designed and delivered a Web-based multilingual solution to support the efforts of CdLS World, an international federation of non-profit organizations committed to assisting those affected by Cornelia de Lange Syndrome (CdLS), a rare congenital disorder. While there is as yet no cure for CdLS, information and access to early therapeutic interventions and therapies is the key to helping children with CdLS reach their full potential. Sapient"s Ask the Doctor - which can be accessed at http://www.cdlsworld.org or through local CdLS country websites - brings a vast online re of up-to-date, relevant medical information to families and medical professionals around the world.
Neurofeedback - also called EEG Biofeedback - is a method used to train brain activity in order to normalize Brain function and treat psychiatric disorders. This treatment method has gained interest over the last 10 years, however the question whether this treatment should be regarded as an Evidence-Based treatment was unanswered until now. Tomorrow a study will be published in the scientific journal "EEG and Clinical Neuroscience" demonstrating that Neurofeedback can indeed be regarded as an evidence-based treatment for Attention Deficit- / Hyperactivity Disorder (ADHD).
Researchers at the University of Rochester Medical Center have found a way to block the genetic flaw at the heart of a common form of muscular dystrophy. The results of the study, which were published in the journal Science, could pave the way for new therapies that essentially reverse the symptoms of the disease.
Mental Health America today commended Senate and House health reform legislation for including mental health and substance use coverage in a benefit package.
"This is Year 20 for America"s Best Hospitals, a tool for patients who need medical sophistication that most facilities are unable to provide," reports U.S. News and World Report. The magazine ranked hospitals based on how well they did in "complex and demanding situations" such as "replacing an 85-year-old"s heart valve, diagnosing and treating a spinal tumor, and dealing with inflammatory bowel disease." Out of a total 4,861 hospitals analyzed, "Only 174 hospitals scored high enough to be ranked in even one of the 16 specialties. And of these, just 21 qualified for [the] Honor Roll by ranking at or near the top in at least six specialties." The ranking list includes the 50 highest scoring hospitals (Comarow, 7/15).
"A hospital that serves thousands of indigent Massachusetts residents sued the state on Wednesday, charging that its costly universal health care law is forcing the hospital to cover too much of the expense of caring for the poor," according to the New York Times.
US researchers have discovered the molecular mechanisms by which the human body metabolizes selenium, a trace element that plays an essential
Yesterday"s Senate HELP Committee"s vote for a health reform bill and the beginning today of the committee markup process in the House of Representatives mark significant steps forward on the path to comprehensive health reform.
Springer, one of the leading publishers in the fields of science, technology and medicine, has signed a co-publishing agreement with the Indian Association of Surgical Oncology (IASO), to launch the society"s official publication, the Indian Journal of Surgical Oncology (IJSO). Dr. Vijay Kumar, Secretary of the Indian Association of Surgical Oncology; Dr. K.S. Gopinath, editor of the IIndian Journal of Surgical Oncology; Dr. William F. Curtis, President of Springer Science+Business Media, LLC; and Sanjiv Goswami, Managing Director of Springer India, signed the agreement at Bangalore.
Consumers may be able to eat longer-lasting, potentially healthier fish fillets if research at Oregon State University makes its way to the supermarket.
Barrow Neurological Institute researchers have identified a novel receptor in the brain that is extremely sensitive to beta-amyloid peptide (AB) and may play a key role in early stages of Alzheimer"s disease.
New research, has revealed that an extract which concentrates specific nutrients from Klamath blue green algae, could provide an effective natural remedy for women looking for an effective alternative to HRT to control mood swings and improve overall wellbeing.
The Health and Safety Executive (HSE) received copies of Lord Gill"s report[1] into the explosion, caused by a leak of liquefied petroleum gas (LPG) on 11 May 2004, when nine people died and many more were injured at the ICL Plastics factory in Maryhill, Glasgow.
Those travelling abroad should take seriously advice to pack their condoms and keep their needles to themselves: research published today in the open access journal Retrovirology shows that tourists, travellers and migrants from Greece, Portugal, Serbia and Spain actively export HIV-1 subtype B to other European nations.
Clarithromycin is currently one of the antibiotics used for eradication of Helicobacter pylori. However, reports of H. pylori resistance to this antibiotic are increasing worldwide. Clarithromycin resistance has been attributed to the presence of mutations in the 23S rRNA gene, a component of the ribosome that is the protein manufacturing machinery of all living cells. There is little information on the prevalence and characteristics of clarithromycin resistance in H. pylori strains isolated from Malaysian patients.
Based on serum bank material, BA profiling was applied in IBD patients and healthy controls which showed that most but not all BA species were decreased to a different extent in CD and UC. BA decreases were highly pronounced in CD patients with surgical interventions in the gut. On the other hand, UC patients with additional liver and gallbladder diseases showed clearly increased levels of those BAs that are synthesized directly in the liver (primary BAs), or subsequently modified by intestinal bacteria (secondary BAs). Furthermore, a marked decrease in the toxic BA lithocholic acid (LCA) was found together with a marked increase in its physiological detoxification product, hyodeoxycholic acid (HDCA), irrespective of the IBD phenotype or clinical manifestation, which showed accelerated detoxification activity in IBD patients. Thus, serum BA profiling might serve as an additional diagnostic tool for IBD characterization and differentiation. In combination with expression profiles of nuclear pregnane X receptor (PXR)-regulated genes, it might allow us to estimate the BA detoxification potential of IBD patients.
Prognosis of pancreatic cancer is poor. Recently, it has been discovered that the grade of tumor angiogenesis is a useful prognostic marker in human cancer, including pancreatic cancer. To establish the grade of tumor angiogenesis by non-invasive imaging may be important clinically. However, there are only a few such reports on pancreatic cancer.
An upcoming G&D paper reveals how two specific matrix metalloproteinase (MMP) proteins contribute to bone metastasis in advanced breast cancer - lending important new insight into the design of clinically useful small molecule inhibitors.
Every 30 seconds a person somewhere in the world loses a lower limb to amputation due to diabetic foot disease.
Nearly 90 per cent of people in the UK back proposals to stop under 18s from using sunbeds according to a new survey by Cancer Research UK.
The Brain Emporium offers Cleveland elders an opportunity to refute the adage "You can"t teach an old dog new tricks."
We use the term ringworm or tinea when referring to several types of contagious fungal infections of the top layer of the skin and scalp, as well as the nails. We call it ringworm because the itchy, red rash has a ring-like appearance. There is no connection between ringworm and worms.
A protein in influenza virus that helps it multiply also damages lung epithelial cells, causing fluid buildup in the lungs, according to new research from the University of Alabama at Birmingham (UAB) and Southern Research Institute . Publishing online this week in the journal of the Federation of American Societies for Experimental Biology, the researchers say the findings give new insight into how flu attacks the lungs and provides targets for new treatments.
One of the aims imposed by the European Union in 2004 is to reduce the number of traffic accidents. However, despite the measures taken by the different administrations and the consequent decrease in the number of accidents, the results for 2010 are not close to those set by Europe. Gerardo Reveriego, a young researcher of the University of Mē”laga, has designed software that informs drivers of the risk situations s/he has while driving. This allows drivers to self-assess themselves and improve their driving behaviour.
At a technical breakfast, Romain Quidant presented his research into the detection and treatment of cancer using gold nanoparticles illuminated with laser light. Quidant, who was recently awarded the Fresnel Prize 2009 that recognizes the highest level of excellence amongst emerging researchers in the field of photonics, is an ICREA researcher at the UPC"s Institute of Photonic Sciences (ICFO) and a fellow of the Cellex Foundation Barcelona.
"As more medical students shun primary care for higher-paid specialties, experts warn of a severe imbalance that could cripple the nation"s health care system," CNN Money reports. Luis Manriquez, a first-year student at the University of Washington School of Medicine wants to become a family doctor, an increasingly rare ambition. He will "probably make one-fourth the salary of a specialist while trying to pay down $140,000 on average in medical school debt." Manriquez says that "primary care physicians are considered to not do as much as specialists. ņ¦ People have told me that generalists are less respected as doctors."
"In a move that caught many public health experts by surprise, the WHO quietly announced Thursday that it would stop tracking swine flu cases and deaths around the world," the New York Times reports. According to the newspaper, the announcement "perplexed some experts, and even baffled a WHO spokesman, Gregory Hartl," who "earlier in the day ņ¦ had confirmed Argentina, with 137 swine flu deaths since June, had surpassed Mexico, where the epidemic began in February, as the country with second largest number of swine flu deaths." While the last WHO updated indicated nearly 95,000 people worldwide had been infected with H1N1, "[m]any epidemiologists have pointed out that, in reality, millions of people have had swine flu, usually in a mild form, so the numbers of laboratory-confirmed cases were actually meaningless" while tests "overwhelmed national laboratories," according to the New York Times (McNeil, 7/16).
The aloe vera plant has a long history of healing power. Its ability to heal burns and cuts and soothe pain has been documented as far back as the 10th century. Legend has it that Cleopatra used aloe vera to keep her skin soft. The modern use of aloe vera was first recognized the 1930s to heal radiation burns. Since then, it has been a common ingredient in ointments that heal sunburn, minor cuts, skin irritation, and many other ailments. Recently, aloe vera has gained some popularity as an active ingredient in tooth gel. Similar to its use on skin, the aloe vera in tooth gels is used to cleanse and soothe teeth and gums, and is as effective as toothpaste to fight cavities, according to the May/June 2009 issue of General Dentistry, the Academy of General Dentistry"s (AGD) clinical, peer-reviewed journal.
Researchers have warned people to beware of the damage that acidic beverages have on teeth. Yet, for some, the damage and problems associated with drinking sodas, citric juices or certain tea may have already begun to take effect. The question remains: What can be done to restore teeth already affected?
The June cover of the Journal of Virology features a photograph of the unusual effects on a cell infected by a virus. Montana State University researchers were the first to view the virus, which they collected from a boiling, acidic spring in Yellowstone.
The American Nurses Association (ANA) reached out to lawmakers Friday, with a letter in support of H.R. 3200 "America"s Affordable Health Choices Act of 2009." After a contingent from ANA took part in a Rose Garden press conference with President Obama July 15th, ANA set out to engage lawmakers, nurses, and other health professionals across the country to voice their commitment to real healthcare reform.
A study which found up to one third of GPs are planning to retire early highlights the need for governments to boost support for general practice, AMA Federal President, Dr Andrew Pesce, said today.
PolyMedix, Inc., an emerging biotechnology company developing acute care products for infectious diseases and acute cardiovascular disorders based on biomimetics, announced that three posters relating to the Company"s heptagonist compounds were presented at the International Society on Thrombosis and Hemostasis Conference. The posters were presented at the conference on July 16, 2009, by PolyMedix"s collaborators at Loyola University.
Yesterday the AMA issued formal endorsement of the House Healthcare Bill. According to Sermo (http://www.sermo.com), the largest online community of physicians in the US, AMA"s endorsement does not reflect the position of practicing physicians.
Diabetes patients taking NovoLog® (insulin aspart [rDNA origin] injection) can now use the insulin in their pump for up to six days following the U.S. Food and Drug Administration (FDA) approval of a labeling change, diabetes care company Novo Nordisk announced today.[i] The previous label allowed for NovoLog® to be stored in the pump reservoir for two days. This makes NovoLog® the first and only rapid-acting insulin with this extended in-use time.
A research team led by the La Jolla Institute for Allergy & Immunology has identified the specific gene which triggers the body to produce disease-fighting antibodies -- a seminal finding that clarifies the exact molecular steps taken by the body to mount an antibody defense against viruses and other pathogens. The finding, published online in the prestigious journal Science, has major implications for the development of new and more effective vaccines. The La Jolla Institute"s Shane Crotty, Ph.D., was the lead scientist on the team, which also included researchers from Yale University.
Studies have estimated that five to
US Oncology, Inc. today announced that US Oncology Research will participate in the BiPar Sciences" Phase III, Multi-center, Open-Label, Randomized Trial of Gemcitabine/Carboplatin (G/C), with or without BSI-201, in patients with Estrogen Receptor (ER), Progesterone Receptor (PR), and HER2-negative metastatic breast cancer.
It is an amazing sight: What looks like a tiny beating heart is actually a piece of synthetic, gauze-like mesh, barely the size of a fingernail, floating in a Petri dish. And yet it keeps squeezing away, nice and rhythmically.
HIV and sexual health charity Terrence Higgins Trust (THT) is pleased to announce the launch of Mambo Online (http://www.mambo.org.uk), a major website dedicated to raising awareness of HIV and sexual health specifically among African communities. The service will go live on 20 July.